Carregando...
RTB lectin-mediated delivery of lysosomal α-L-iduronidase mitigates disease manifestations systemically including the central nervous system
Mucopolysaccharidosis type I (MPS I) is a lysosomal disease resulting from deficiency in the α-L-iduronidase (IDUA) hydrolase and subsequent accumulation of glycosaminoglycan (GAG). Clinically, enzyme replacement therapy (ERT) with IDUA achieves negligible neurological benefits presumably due to blo...
Na minha lista:
| Publicado no: | Mol Genet Metab |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808854/ https://ncbi.nlm.nih.gov/pubmed/29198892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2017.11.013 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|