Silencing steroid receptor coactivator-1 in the nucleus of the solitary tract reduces estrogenic effects on feeding and apolipoprotein A-IV expression

We previously found that 17β-estradiol (E2) stimulates apolipoprotein A-IV (apoA-IV) gene expression in the nucleus of the solitary tract (NTS) of lean ovariectomized (OVX) rodents. Here we report that in the NTS of high-fat diet-induced obese (DIO) rats, the apoA-IV mRNA level is significantly redu...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Shen, Ling, Liu, Yin, Tso, Patrick, Wang, David Q.-H., Davidson, W. Sean, Woods, Stephen C., Liu, Min
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808769/
https://ncbi.nlm.nih.gov/pubmed/29263093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000237
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