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Identification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation

Spider venom neurotoxins and cytolytic peptides are expressed as elongated precursor peptides, which are post-translationally processed by proteases to yield the active mature peptides. The recognition motifs for these processing proteases, first published more than 10 years ago, include the process...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Langenegger, Nicolas, Koua, Dominique, Schürch, Stefan, Heller, Manfred, Nentwig, Wolfgang, Kuhn-Nentwig, Lucia
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808768/
https://ncbi.nlm.nih.gov/pubmed/29269415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.810911
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