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Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2–related factors 1 and 2 (NRF1 and NRF2)

Nuclear factor erythroid-2–related factor 1 (NRF1) and NRF2 are essential for maintaining redox homeostasis and coordinating cellular stress responses. They are highly homologous transcription factors that regulate the expression of genes bearing antioxidant-response elements (AREs). Genetic ablatio...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Tian, Wang, Rojo de la Vega, Montserrat, Schmidlin, Cody J., Ooi, Aikseng, Zhang, Donna D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808764/
https://ncbi.nlm.nih.gov/pubmed/29255090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000428
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