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Cathepsin B regulates hepatic lipid metabolism by cleaving liver fatty acid–binding protein

Synthesis and secretion of hepatic triglycerides (TAG) associated with very-low-density lipoprotein (VLDL) play a major role in maintaining overall lipid homeostasis. This study aims to identify factors affecting synthesis and secretion of VLDL-TAG using the growth hormone–deficient Ames dwarf mouse...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Thibeaux, Simeon, Siddiqi, Shaila, Zhelyabovska, Olga, Moinuddin, Faisal, Masternak, Michal M., Siddiqi, Shadab A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808755/
https://ncbi.nlm.nih.gov/pubmed/29259130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.778365
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