Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors

INTRODUCTION: The development of nanodrug carriers utilizing tumor microenvironment has become a hotspot in reversing multidrug resistance (MDR). MATERIALS AND METHODS: This study synthesized a redox-sensitive copolymer, Pluronic F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lin, Jing, Zhao, Chaoyue, Liu, Cuijuan, Fu, Shiyao, Han, Luying, Lu, Xinping, Yang, Chunrong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808690/
https://ncbi.nlm.nih.gov/pubmed/29445276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S152395
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