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Enhancing Evolutionary Couplings with Deep Convolutional Neural Networks

While genes are defined by sequence, in biological systems a protein’s function is largely determined by its three-dimensional structure. Evolutionary information embedded within multiple sequence alignments provides a rich source of data for inferring structural constraints on macromolecules. Still...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Syst
Main Authors: Liu, Yang, Palmedo, Perry, Ye, Qing, Berger, Bonnie, Peng, Jian
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808454/
https://ncbi.nlm.nih.gov/pubmed/29275173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.11.014
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