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Enhancing Evolutionary Couplings with Deep Convolutional Neural Networks
While genes are defined by sequence, in biological systems a protein’s function is largely determined by its three-dimensional structure. Evolutionary information embedded within multiple sequence alignments provides a rich source of data for inferring structural constraints on macromolecules. Still...
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| Publicado no: | Cell Syst |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808454/ https://ncbi.nlm.nih.gov/pubmed/29275173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.11.014 |
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