Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice

The early life microbiome plays important roles in host immunological and metabolic development. Because the incidence of type 1 diabetes (T1D) has been increasing substantially in recent decades, we hypothesized that early-life antibiotic use alters gut microbiota, which predisposes to disease. Usi...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Livanos, Alexandra E., Greiner, Thomas U., Vangay, Pajau, Pathmasiri, Wimal, Stewart, Delisha, McRitchie, Susan, Li, Huilin, Chung, Jennifer, Sohn, Jiho, Kim, Sara, Gao, Zhan, Barber, Cecily, Kim, Joanne, Ng, Sandy, Rogers, Arlin B., Sumner, Susan, Zhang, Xue-Song, Cadwell, Ken, Knights, Dan, Alekseyenko, Alexander, Bäckhed, Fredrik, Blaser, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808443/
https://ncbi.nlm.nih.gov/pubmed/27782139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.140
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