Genetic Regulation of Guanylate-Binding Proteins 2b and 5 during Leishmaniasis in Mice

Interferon-induced GTPases [guanylate-binding proteins (GBPs)] play an important role in inflammasome activation and mediate innate resistance to many intracellular pathogens, but little is known about their role in leishmaniasis. We therefore studied expression of Gbp2b/Gbp1 and Gbp5 mRNA in skin,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sohrabi, Yahya, Volkova, Valeryia, Kobets, Tatyana, Havelková, Helena, Krayem, Imtissal, Slapničková, Martina, Demant, Peter, Lipoldová, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808352/
https://ncbi.nlm.nih.gov/pubmed/29467757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00130
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