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Darunavir/cobicistat showing similar effectiveness as darunavir/ritonavir monotherapy despite lower trough concentrations
INTRODUCTION: When darunavir (DRV) 800 mg is boosted with 150 mg cobicistat (DRV (cobi)), DRV trough concentration (C(trough)) is about 30% lower as compared to 100 mg ritonavir (DRV (rtv)). DRV (cobi) shows similar virological efficacy as DRV (rtv) when combined with two nucleos(t)ide analogue reve...
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| Veröffentlicht in: | J Int AIDS Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808101/ https://ncbi.nlm.nih.gov/pubmed/29430854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jia2.25072 |
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