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Associations of Autoimmunity, Immunodeficiency, Lymphomagenesis, and Gut Microbiota in Mice with Knockins for a Pathogenic Autoantibody

A number of mouse strains transgenic for B-cell receptors specific for nucleic acids or other autoantigens have been generated to understand how autoreactive B cells are regulated in normal and autoimmune mice. Previous studies of nonautoimmune C57BL/6 mice heterozygous for both the IgH and IgL knoc...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Jain, Shweta, Ward, Jerrold M., Shin, Dong-Mi, Wang, Hongsheng, Naghashfar, Zohreh, Kovalchuk, Alexander L., Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807958/
https://ncbi.nlm.nih.gov/pubmed/28727987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.05.017
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