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Novel Modifications of Glycopeptide Antibiotics via Total Synthesis

[Image: see text] Although vancomycin has been in clinical use since the late 1950s, resistance due to alteration in the target microbe’s peptidoglycan can vary significantly, reducing its activity. Total synthesis of derivatives has now led to a molecule with very significant activity against resis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Med Chem Lett
Prif Awdur: Newman, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807861/
https://ncbi.nlm.nih.gov/pubmed/29456789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00029
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