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FMLRC: Hybrid long read error correction using an FM-index

BACKGROUND: Long read sequencing is changing the landscape of genomic research, especially de novo assembly. Despite the high error rate inherent to long read technologies, increased read lengths dramatically improve the continuity and accuracy of genome assemblies. However, the cost and throughput...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Wang, Jeremy R., Holt, James, McMillan, Leonard, Jones, Corbin D.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807796/
https://ncbi.nlm.nih.gov/pubmed/29426289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2051-3
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