The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever via Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice

Neurokinin (NK) signaling is involved in various inflammatory processes. A common manifestation of systemic inflammation is fever, which is usually induced in animal models with the administration of bacterial lipopolysaccharide (LPS). A role for the NK1 receptor was shown in LPS-induced fever, but...

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Udgivet i:Front Immunol
Main Authors: Pakai, Eszter, Tekus, Valeria, Zsiboras, Csaba, Rumbus, Zoltan, Olah, Emoke, Keringer, Patrik, Khidhir, Nora, Matics, Robert, Deres, Laszlo, Ordog, Katalin, Szentes, Nikolett, Pohoczky, Krisztina, Kemeny, Agnes, Hegyi, Peter, Pinter, Erika, Garami, Andras
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807668/
https://ncbi.nlm.nih.gov/pubmed/29459872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00166
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