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Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research

Saposin-derived lipid nanoparticles (SapNPs) are a new alternative tool for membrane protein reconstitution. Here we demonstrate the potential and advantages of SapNPs. We show that SapA has the lowest lipid specificity for SapNP formation. These nanoparticles are modular and offer a tunable range o...

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Detalles Bibliográficos
Publicado en:Structure
Main Authors: Flayhan, Ali, Mertens, Haydyn D.T., Ural-Blimke, Yonca, Martinez Molledo, Maria, Svergun, Dmitri I., Löw, Christian
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807053/
https://ncbi.nlm.nih.gov/pubmed/29413323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.01.007
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