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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

During gastrulation epiblast cells exit pluripotency as they specify and spatially arrange the three germ layers of the embryo. Similarly, human pluripotent stem cells (PSCs) undergo spatially organized fate specification on micropatterned surfaces. Since in vivo validation is not possible for the h...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Morgani, Sophie M, Metzger, Jakob J, Nichols, Jennifer, Siggia, Eric D, Hadjantonakis, Anna-Katerina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807051/
https://ncbi.nlm.nih.gov/pubmed/29412136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32839
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