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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning
During gastrulation epiblast cells exit pluripotency as they specify and spatially arrange the three germ layers of the embryo. Similarly, human pluripotent stem cells (PSCs) undergo spatially organized fate specification on micropatterned surfaces. Since in vivo validation is not possible for the h...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807051/ https://ncbi.nlm.nih.gov/pubmed/29412136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32839 |
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