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Immunological effects of everolimus in patients with metastatic renal cell cancer

The mammalian target of rapamycin (mTOR) is a crucial kinase present in all cells. Besides its role in the regulation of cell-growth, proliferation, angiogenesis, and survival of malignant tumors, mTOR additionally plays an important role in immune regulation by controlling the balance between effec...

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Bibliografiska uppgifter
I publikationen:Int J Immunopathol Pharmacol
Huvudupphovsmän: Huijts, Charlotte M, Santegoets, Saskia J, de Jong, Tamarah D, Verheul, Henk M, de Gruijl, Tanja D, van der Vliet, Hans J
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806813/
https://ncbi.nlm.nih.gov/pubmed/28988508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0394632017734459
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