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Downregulation of L-arginine metabolism in dendritic cells induces tolerance to exogenous antigen

Dendritic cells (DC) are potential tools for therapeutic applications and several strategies to generate tolerogenic DCs are under investigation. When activated by cytokines and microbial products, DCs express mediators that modulate immune responses. In this regard, the metabolites generated by the...

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Detalhes bibliográficos
Publicado no:Int J Immunopathol Pharmacol
Main Authors: Simioni, Patricia U, Fernandes, Luis GR, Tamashiro, Wirla MSC
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806782/
https://ncbi.nlm.nih.gov/pubmed/27903843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0394632016678873
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