Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes

BACKGROUND: Follicle stimulating hormone and testosterone stimulate Sertoli cells to support germ cell function and differentiation. During mini-puberty, when gonadotropin (GnRH) stimulates increases in plasma luteinizing hormone (LH) and testosterone levels, gonocytes are transformed into Ad sperma...

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Vydáno v:Basic Clin Androl
Hlavní autoři: Gegenschatz-Schmid, Katharina, Verkauskas, Gilvydas, Demougin, Philippe, Bilius, Vytautas, Dasevicius, Darius, Stadler, Michael B., Hadziselimovic, Faruk
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806254/
https://ncbi.nlm.nih.gov/pubmed/29456864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12610-018-0067-1
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