Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X:BOT): a multicentre, open-label, randomised controlled trial

BACKGROUND: Extended-release naltrexone (XR-NTX), an opioid antagonist, and sublingual buprenorphine-naloxone (BUP-NX), a partial opioid agonist, are pharmacologically and conceptually distinct interventions to prevent opioid relapse. We aimed to estimate the difference in opioid relapse-free surviv...

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發表在:Lancet
Main Authors: Lee, Joshua D, Nunes, Edward V, Novo, Patricia, Bachrach, Ken, Bailey, Genie L, Bhatt, Snehal, Farkas, Sarah, Fishman, Marc, Gauthier, Phoebe, Hodgkins, Candace C, King, Jacquie, Lindblad, Robert, Liu, David, Matthews, Abigail G, May, Jeanine, Peavy, K Michelle, Ross, Stephen, Salazar, Dagmar, Schkolnik, Paul, Shmueli-Blumberg, Dikla, Stablein, Don, Subramaniam, Geetha, Rotrosen, John
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806119/
https://ncbi.nlm.nih.gov/pubmed/29150198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)32812-X
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