A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression

One commonly performed bioinformatics task is to infer functional regulation of transcription factors by observing differential expression under a knockout, and integrating DNA binding information of that transcription factor.   However, until now, this task has required dedicated bioinformatics sup...

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Bibliographic Details
Published in:F1000Res
Main Authors: Carlin, Daniel, Kosnicki, Kassi, Garamszegi, Sara, Ideker, Trey, Thorvaldsdóttir, Helga, Reich, Michael, Mesirov, Jill
Format: Artigo
Language:Inglês
Published: F1000 Research Limited 2018
Subjects:
Method Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806050/
https://ncbi.nlm.nih.gov/pubmed/29487738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11616.2
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