Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial

BACKGROUND: Infants in the UK were first offered a pneumococcal conjugate vaccine (PCV7) in 2006, given at 2 and 4 months of age and a booster dose at 13 months (2 + 1 schedule). A 13-valent vaccine (PCV13) replaced PCV7 in 2010. We aimed to compare the post-booster antibody response in UK infants g...

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Detalhes bibliográficos
Publicado no:Lancet Infect Dis
Main Authors: Goldblatt, David, Southern, Jo, Andrews, Nick J, Burbidge, Polly, Partington, Jo, Roalfe, Lucy, Valente Pinto, Marta, Thalasselis, Vasilli, Plested, Emma, Richardson, Hayley, Snape, Matthew D, Miller, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science ;, The Lancet Pub. Group 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805912/
https://ncbi.nlm.nih.gov/pubmed/29174323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(17)30654-0
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