Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

BACKGROUND: Retrospective studies provide conflicting interpretations of the effect of inherited genetic factors on the prognosis of patients with breast cancer. The primary aim of this study was to determine the effect of a germline BRCA1 or BRCA2 mutation on breast cancer outcomes in patients with...

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Publicado no:Lancet Oncol
Main Authors: Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Pub. Group 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805863/
https://ncbi.nlm.nih.gov/pubmed/29337092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30891-4
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