Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance

Multidrug resistance is a major challenge to cancer chemotherapy. The multidrug resistance phenotype is associated with the overexpression of the adenosine triphosphate (ATP)-driven transmembrane efflux pumps in cancer cells. Here, we report a lipid membrane-coated silica-carbon (LSC) hybrid nanopar...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Wang, Hai, Gao, Zan, Liu, Xuanyou, Agarwal, Pranay, Zhao, Shuting, Conroy, Daniel W., Ji, Guang, Yu, Jianhua, Jaroniec, Christopher P., Liu, Zhenguo, Lu, Xiongbin, Li, Xiaodong, He, Xiaoming
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805731/
https://ncbi.nlm.nih.gov/pubmed/29422620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02915-8
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