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Multi-Organ Microphysiological Systems for Drug Development: Strategies, Advances and Challenges

Traditional cell culture and animal models utilized for preclinical drug screening have led to high attrition rates of drug candidates in clinical trials due to their low predictive power for human response. Alternative models using human cells to build in vitro biomimetics of the human body with ph...

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Podrobná bibliografie
Vydáno v:Adv Healthc Mater
Hlavní autoři: Wang, Ying I, Carmona, Carlos, Hickman, James J, Shuler, Michael L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805562/
https://ncbi.nlm.nih.gov/pubmed/29205920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201701000
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