Sirtuin1 is required for proper trophoblast differentiation and placental development in mice

INTRODUCTION: Placental insufficiency, arising from abnormal trophoblast differentiation and function, is a major cause of fetal growth restriction. Sirtuin-1 (Sirt1) is a ubiquitously-expressed NAD-dependent protein deacetylase which plays a key role in numerous cellular processes, including cellul...

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Detalhes bibliográficos
Publicado no:Placenta
Main Authors: Rajan, Kanaga Arul Nambi, Khater, Marwa, Soncin, Francesca, Pizzo, Donald, Moretto-Zita, Matteo, Pham, Jonathan, Stus, Orysya, Iyer, Pooja, Tache, Veronique, Laurent, Louise C., Parast, Mana M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805473/
https://ncbi.nlm.nih.gov/pubmed/29405961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2017.12.002
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