Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits

OBJECTIVE: Cholesteryl ester transfer protein (CETP) plays an important role in lipoprotein metabolism; however, whether inhibition of CETP activity can prevent cardiovascular disease remains controversial. APPROACH AND RESULTS: We generated CETP knockout (KO) rabbits by zinc finger nuclease gene ed...

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I publikationen:Arterioscler Thromb Vasc Biol
Huvudupphovsmän: Zhang, Jifeng, Niimi, Manabu, Yang, Dongshan, Liang, Jingyan, Xu, Jie, Kimura, Tokuhide, Mattew, Anna V., Guo, Yanhong, Fan, Yanbo, Zhu, Tianqing, Song, Jun, Ackermann, Rose, Koike, Yui, Schwendeman, Anna, Lai, Liangxue, Pennathur, Subramaniam, Garcia-Barrio, Minerva, Fan, Jianglin, Chen, Y. Eugene
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805397/
https://ncbi.nlm.nih.gov/pubmed/28428219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309114
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