A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch

Chronic pain and itch are common hypersensitivity syndromes that are affected by endogenous mediators. We applied a systems-based, translational approach to predict, discover, and characterize mediators of pain and itch that are regulated by diet and inflammation. Profiling of tissue-specific precur...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Ramsden, Christopher E., Domenichiello, Anthony F., Yuan, Zhi-Xin, Sapio, Matthew R., Keyes, Gregory S., Mishra, Santosh K., Gross, Jacklyn R., Majchrzak-Hong, Sharon, Zamora, Daisy, Horowitz, Mark S., Davis, John M., Sorokin, Alexander V., Dey, Amit, LaPaglia, Danielle M., Wheeler, Joshua J., Vasko, Michael R., Mehta, Nehal N., Mannes, Andrew J., Iadarola, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805383/
https://ncbi.nlm.nih.gov/pubmed/28831021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal5241
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