Assembly of functionally integrated human forebrain spheroids

The development of the nervous system involves a coordinated succession of events including the migration of GABAergic neurons from ventral to dorsal forebrain and their integration into cortical circuits. However, these interregional interactions have not yet been modelled with human cells. Here, w...

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Gepubliceerd in:Nature
Hoofdauteurs: Birey, Fikri, Andersen, Jimena, Makinson, Christopher D., Islam, Saiful, Wei, Wu, Huber, Nina, Fan, H. Christina, Cordes Metzler, Kimberly R., Panagiotakos, Georgia, Thom, Nicholas, O’Rourke, Nancy A., Steinmetz, Lars M., Bernstein, Jonathan A., Hallmayer, Joachim, Huguenard, John R., Pașca, Sergiu P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805137/
https://ncbi.nlm.nih.gov/pubmed/28445465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22330
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