High-Yielding Automated Convergent Synthesis of No-Carrier-Added [(11)C-Carbonyl]-Labeled Amino Acids Using the Strecker Reaction

A new variant of the Strecker synthesis using no-carrier-added [(11)C]cyanide for the synthesis of radiolabeled amino acids is described. The protocol is fully automated using a radiochemistry synthesis module and applied to the production of a number of new PET radiotracers. [(11)C-Carbonyl]sarcosi...

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Bibliographic Details
Published in:Synlett
Main Authors: Xing, Junhao, Brooks, Allen F., Fink, Dylan, Zhang, Huibin, Piert, Morand R., Scott, Peter J. H., Shao, Xia
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804752/
https://ncbi.nlm.nih.gov/pubmed/29430080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1588638
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