Podocyte-derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36

Tubulointerstitial fibrosis is a hallmark of advanced diabetic kidney disease that is linked to a decline in renal function, however the pathogenic mechanisms are poorly understood. Microparticles (MPs) are 100–1000 nm vesicles shed from injured cells that are implicated in intercellular signalling....

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Dettagli Bibliografici
Pubblicato in:J Extracell Vesicles
Autori principali: Munkonda, Mercedes N., Akbari, Shareef, Landry, Chloe, Sun, Suzy, Xiao, Fengxia, Turner, Maddison, Holterman, Chet E., Nasrallah, Rania, Hébert, Richard L., Kennedy, Christopher R. J., Burger, Dylan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804677/
https://ncbi.nlm.nih.gov/pubmed/29435202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2018.1432206
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