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SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation

Epigenetic regulation of chromatin states is thought to control gene expression programs during lineage specification. However, the roles of repressive histone modifications such as trimethylated histone lysine 20 (H4K20me3) in development and genome stability are largely unknown. Here we show that...

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Foilsithe in:Cancer Res
Main Authors: Kidder, Benjamin L., He, Runsheng, Wangsa, Darawalee, Padilla-Nash, Hesed M., Bernardo, M. Margarida, Sheng, Shijie, Ried, Thomas, Zhao, Keji
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804482/
https://ncbi.nlm.nih.gov/pubmed/28951459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0828
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