Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System

The spontaneously diabetic Torii (SDT) rat is of increasing preclinical interest because of its similarities to human type 2 diabetic retinopathy (DR). The system formed by urokinase-type plasminogen activator (uPA) and its receptor (uPAR) is a player in blood-retinal barrier (BRB) breakdown in DR....

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Cammalleri, Maurizio, Dal Monte, Massimo, Locri, Filippo, Marsili, Stefania, Lista, Liliana, De Rosa, Mario, Pavone, Vincenzo, Rusciano, Dario, Bagnoli, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804371/
https://ncbi.nlm.nih.gov/pubmed/29464181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2904150
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