Pharmacologic Reprogramming Designed to Induce a Warburg Effect in Porcine Fetal Fibroblasts Alters Gene Expression and Quantities of Metabolites from Conditioned Media Without Increased Cell Proliferation

The Warburg effect is a metabolic phenomenon characterized by increased glycolytic activity, decreased mitochondrial oxidative phosphorylation, and the production of lactate. This metabolic phenotype is characterized in rapidly proliferative cell types such as cancerous cells and embryonic stem cell...

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Bibliografiske detaljer
Udgivet i:Cell Reprogram
Main Authors: Mordhorst, Bethany R., Murphy, Stephanie L., Ross, Renee M., Samuel, Melissa S., Salazar, Shirley Rojas, Ji, Tieming, Behura, Susanta K., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804098/
https://ncbi.nlm.nih.gov/pubmed/29412741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2017.0040
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