Whole-exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder

Panic disorder (PD) is characterized by recurrent and unexpected panic attacks, subsequent anticipatory anxiety, and phobic avoidance. Recent epidemiological and genetic studies have revealed that genetic factors contribute to the pathogenesis of PD. We performed whole-exome sequencing on one Japane...

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Publié dans:Transl Psychiatry
Auteurs principaux: Morimoto, Yoshiro, Shimada-Sugimoto, Mihoko, Otowa, Takeshi, Yoshida, Shintaro, Kinoshita, Akira, Mishima, Hiroyuki, Yamaguchi, Naohiro, Mori, Takatoshi, Imamura, Akira, Ozawa, Hiroki, Kurotaki, Naohiro, Ziegler, Christiane, Domschke, Katharina, Deckert, Jürgen, Umekage, Tadashi, Tochigi, Mamoru, Kaiya, Hisanobu, Okazaki, Yuji, Tokunaga, Katsushi, Sasaki, Tsukasa, Yoshiura, Koh-ichiro, Ono, Shinji
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804028/
https://ncbi.nlm.nih.gov/pubmed/29391400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0088-0
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