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A Case Report of Compound Heterozygous CYP24A1 Mutations Leading to Nephrolithiasis Successfully Treated with Ketoconazole

CYP24A1 is an enzyme that inactivates vitamin D. Loss-of-function mutations in this enzyme are rare but have been linked with idiopathic infantile hypercalcemia as well as adult-onset nephrocalcinosis and nephrolithiasis. Genetic testing for this mutation should be considered in the presence of calc...

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Detalhes bibliográficos
Publicado no:Case Rep Nephrol Dial
Main Authors: Davidson Peiris, Emma, Wusirika, Raghav
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803692/
https://ncbi.nlm.nih.gov/pubmed/29457022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000485243
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