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Molecular basis for potentiation of Cx36 gap junction channel conductance by n-alcohols and general anesthetics

In our recent study, we have demonstrated that short carbon chain n-alcohols (up to octanol) stimulated while long carbon chain n-alcohols inhibited the conductance of connexin (Cx) 36 (Cx36) gap junction (GJ) channels. In contrast, GJ channels composed of other types of Cxs all were inhibited by n-...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Raškevičius, Vytautas, Jotautis, Vaidas, Rimkutė, Lina, Marandykina, Alina, Kazokaitė, Mintautė, Kairys, Visvaldas, Skeberdis, Vytenis Arvydas
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803492/
https://ncbi.nlm.nih.gov/pubmed/29298877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171323
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