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The Role of Extracellular Matrix Stiffness in Megakaryocyte Development and Function

The extracellular matrix (ECM) is a key acellular structure in constant remodeling to provide tissue cohesion and rigidity. Deregulation of the balance between matrix deposition, degradation and crosslinking results in fibrosis. Bone marrow fibrosis (BMF) is associated with several malignant and non...

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Detalhes bibliográficos
Publicado no:Am J Hematol
Main Authors: Leiva, Orly, Leon, Catherine, Ng, Seng Kah, Mangin, Pierre, Gachet, Christian, Ravid, Katya
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803306/
https://ncbi.nlm.nih.gov/pubmed/29247535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25008
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