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The Role of Extracellular Matrix Stiffness in Megakaryocyte Development and Function

The extracellular matrix (ECM) is a key acellular structure in constant remodeling to provide tissue cohesion and rigidity. Deregulation of the balance between matrix deposition, degradation and crosslinking results in fibrosis. Bone marrow fibrosis (BMF) is associated with several malignant and non...

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Dettagli Bibliografici
Pubblicato in:Am J Hematol
Autori principali: Leiva, Orly, Leon, Catherine, Ng, Seng Kah, Mangin, Pierre, Gachet, Christian, Ravid, Katya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803306/
https://ncbi.nlm.nih.gov/pubmed/29247535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25008
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