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Better agonist for the opioid receptors
This commentary highlights the recent work published in journal Nature on the structural based discovery of novel analgesic compounds for opioid receptors with minimal effects. Manglik et al. selectively targeted the Gi based μOR pathway instead of the β-arrestin pathway of the opioids. The computat...
Guardat en:
| Publicat a: | Chem Cent J |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer International Publishing
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803155/ https://ncbi.nlm.nih.gov/pubmed/29417377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0383-8 |
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