BACHD rats expressing full-length mutant huntingtin exhibit differences in social behavior compared to wild-type littermates

BACKGROUND: Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without any cure to slow down or stop the progress of the disease. The BACHD rat model for HD carrying the human full-length mutant huntin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Manfré, Giuseppe, Novati, Arianna, Faccini, Ilaria, Rossetti, Andrea C., Bosch, Kari, Molteni, Raffaella, Riva, Marco A., Van der Harst, Johanneke E., Nguyen, Huu Phuc, Homberg, Judith R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802907/
https://ncbi.nlm.nih.gov/pubmed/29415038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192289
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