The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer

BACKGROUND: BRCA2-associated breast and ovarian cancers are sensitive to platinum-based chemotherapy. It is unknown whether BRCA2-associated prostate cancer responds favorably to such treatment. METHODS: Retrospective analysis of a single-institution cohort of men with castration-resistant metastati...

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Udgivet i:Cancer
Main Authors: Pomerantz, Mark M., Spisák, Sandor, Jia, Li, Cronin, Angel M., Csabai, Istvan, Ledet, Elisa, Sartor, A. Oliver, Rainville, Irene, O’Connor, Edward, Herbert, Zachary T., Szállási, Zoltan, Oh, William K., Kantoff, Philip W., Garber, Judy E., Schrag, Deborah, Kibel, Adam S., Freedman, Matthew L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802871/
https://ncbi.nlm.nih.gov/pubmed/28608931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30808
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