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FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice

Insulin coordinates the complex response to feeding, affecting numerous metabolic and hormonal pathways. Forkhead box protein O1 (FoxO1) is one of several signaling molecules downstream of insulin; FoxO1 drives gluconeogenesis and is suppressed by insulin. To determine the role of FoxO1 in mediating...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Ling, Alisha V., Gearing, Mary E., Semova, Ivana, Shin, Dong-Ju, Clements, Rebecca, Lai, Zon W., Biddinger, Sudha B.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802805/
https://ncbi.nlm.nih.gov/pubmed/29300910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00870
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