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Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment

Disturbed activity patterns in cortical networks contribute to the pathophysiology of schizophrenia (SZ). Several lines of evidence implicate NMDA receptor hypofunction in SZ, and blocking NMDA receptor signaling during early neurodevelopment produces cognitive deficits in rodent models that resembl...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Seshadri, Saurav, Klaus, Andreas, Winkowski, Daniel E., Kanold, Patrick O., Plenz, Dietmar
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802445/
https://ncbi.nlm.nih.gov/pubmed/29317600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0060-z
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