The nonlinear relationship between cerebrospinal fluid Aβ(42) and tau in preclinical Alzheimer’s disease

Cerebrospinal fluid (CSF) studies consistently show that CSF levels of amyloid-beta 1–42 (Aβ(42)) are reduced and tau levels increased prior to the onset of cognitive decline related to Alzheimer’s disease (AD). However, the preclinical prediction accuracy for low CSF Aβ(42) levels, a surrogate for...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: de Leon, Mony J., Pirraglia, Elizabeth, Osorio, Ricardo S., Glodzik, Lidia, Saint-Louis, Les, Kim, Hee-Jin, Fortea, Juan, Fossati, Silvia, Laska, Eugene, Siegel, Carole, Butler, Tracy, Li, Yi, Rusinek, Henry, Zetterberg, Henrik, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802432/
https://ncbi.nlm.nih.gov/pubmed/29415068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191240
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