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Treatment with Shuyu capsule increases 5-HT1AR level and activation of cAMP-PKA-CREB pathway in hippocampal neurons treated with serum from a rat model of depression
Depressive disorder (DD) is one of the typical affective disorders with a high morbidity, high suicide rate and high recurrence rate. Dysfunction of the 5-hydroxytryptamine 1A receptor (5-HT1AR) in the brain may serve an important role in the pathogenesis of DD. Currently, selective serotonin reupta...
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Published in: | Mol Med Rep |
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Main Authors: | , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
D.A. Spandidos
2018
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5802157/ https://ncbi.nlm.nih.gov/pubmed/29286104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.8339 |
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