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Fate of Antibody-Drug Conjugates in Cancer Cells

Antibody-Drug Conjugates (ADCs) are a class of cancer therapeutics that combines antigen specificity and potent cytotoxicity in a single molecule as they are comprised of an engineered antibody linked chemically to a cytotoxic drug. Four ADCs have received approval by the Food and Drug Administratio...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chalouni, Cécile, Doll, Sophia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802061/
https://ncbi.nlm.nih.gov/pubmed/29409507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0667-1
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