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The Art of War: harnessing the epigenome against cancer

Histone chaperones are indispensable regulators of chromatin structure and function. Recent work has shown that they are frequently mis-regulated in cancer, which can have profound consequences on tumor growth and survival. Here, we focus on chaperones for the essential H3 histone variants H3.3 and...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Nye, Jonathan, Melters, Daniël P., Dalal, Yamini
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801563/
https://ncbi.nlm.nih.gov/pubmed/29479426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12833.1
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