FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal parenchymal lung disease with limited therapeutic options, with fibroblast‐to‐myofibroblast transdifferentiation and hyperproliferation playing a major role. Investigating ex vivo‐cultured (myo)fibroblasts from human IPF lungs as well as...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Al‐Tamari, Hamza M, Dabral, Swati, Schmall, Anja, Sarvari, Pouya, Ruppert, Clemens, Paik, Jihye, DePinho, Ronald A, Grimminger, Friedrich, Eickelberg, Oliver, Guenther, Andreas, Seeger, Werner, Savai, Rajkumar, Pullamsetti, Soni S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801513/
https://ncbi.nlm.nih.gov/pubmed/29217661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606261
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