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Modulation of Sox10, HIF-1α, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult

Premature infants are at an increased risk of developing cognitive and motor handicaps due to chronic hypoxia. Although the current therapies have reduced the incidence of these handicaps, untoward side effects abound. Using a murine model of sublethal hypoxia, we demonstrated reduction in several t...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Li, Qi, Tsuneki, Masayuki, Krauthammer, Michael, Couture, Rachael, Schwartz, Michael, Madri, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801488/
https://ncbi.nlm.nih.gov/pubmed/26209807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.05.016
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