Donor Genotype in the Interleukin-7 Receptor α-Chain Predicts Risk of Graft-versus-Host Disease and Cytomegalovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation

The efficacy of allogeneic hematopoietic stem cell transplantation (HSCT) is challenged by acute and chronic graft-versus-host disease (aGVHD and cGVHD) and viral infections due to long-lasting immunodeficiency. Interleukin-7 (IL-7) is a cytokine essential for de novo T cell generation in thymus and...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kielsen, Katrine, Enevold, Christian, Heilmann, Carsten, Sengeløv, Henrik, Pedersen, Anders Elm, Ryder, Lars P., Müller, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801419/
https://ncbi.nlm.nih.gov/pubmed/29456530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00109
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